List of Episodes/Season 45

Season 45 will feature 26 episodes, including 5 two-part specials, four half-hour specials and four three-minute shorts. This season will air its first episode on September 28, 2076, and this season will air its last episode on November 3, 2077. During the middle of the season, TheJasbre202 left Swaner (A fan of the show) to take over the show.

At episode 21b, Fox joined Nickelodeon and Viacom to make a Family Guy crossover. However, if somebody uploads the episode to Youtube, an email comes and it says the video will have ads.